Egg Allergies

An average of two percent of the population under age five develops an egg allergy. However, most children outgrow their egg allergy by late childhood.

Despite the allergenicity of foods such as eggs, experts do not encourage avoiding these foods when introducing solids to infants.  According to the 2016 National Academies of Science, Engineering, & Medicine food allergy report, there may be “benefits of introducing allergenic foods in the first year of life to infants when a child is developmentally ready: around 6 months of age, and not before 4 months.  This is based on studies showing a possible decrease in the development of food allergies when food allergens are introduced at 4 to 6 months of age.  This advice is consistent with recommendations from the American Academy of Pediatrics.

Additional information on all food allergies and their symptoms is available at FARE-Food Allergy Research & Education and the National Institute of Allergy and Infectious Diseases.

Eggs for infants and toddlers

Tricking the Body-Against Peanut and Egg Proteins Allergens

Researchers in a new preclinical study for Northwestern Medicine have tricked the immune system. They have figured out how to turn off a life threatening allergic response to peanuts (nut proteins). The investigators used mice (that were bred to mimic one with severe food allergies) and attached peanut proteins to leucocytes and reintroduced them into the mice’s bodies. What happened next? The mice ingested a peanut extract and did not have an allergic reaction.

In a second phase of the study, the researchers successfully desensitized mice to egg proteins. The Northwestern researchers used the same tactic with an egg protein. They attached the proteins to white blood cells and infused the cells back into the mice. The mice then inhaled the asthma-provoking egg protein and their lungs did not become inflamed. Dr. Paul J. Bryce, Department of Microbiology-Immunology, Feinberg School of Medicine,noted that it appears that this approach can be used to target multiple food allergies at one time.

Each year there are between 15,000 and 30,000 episodes of food-induced anaphylaxis and 100 to 200 related deaths in the United States, according to the National Institutes of Health. This study may be the link regulating allergic diseases. To quote Dr. Stephen D Miller, the Judy Gugenheim Research Professor at the Feinberg School: “This is an exciting new way in which we can regulate specific allergic diseases and may eventually be used in a clinical setting for patients.”

If this were successful in clinical settings, what would it look like? People with food allergies would not have to worry everyday about coming in contact with the allergen causing food. Also, it would mean that people would be able to enjoy the “allergen causing foods” without risk!